Molecular Formula | C16H22ClN3O |
Molar Mass | 307.82 |
Density | 1.14g/cm3 |
Melting Point | 102-105 ºC |
Boling Point | 475.4°C at 760 mmHg |
Flash Point | 241.3°C |
Water Solubility | 32 MG/L AT 20 ºC |
Solubility | At 20°C, water 32mg/L(pH 7), dichloromethane> 200g/L, hexane <0.1g/L, isopropanol, toluene 50~100g/L. |
Vapor Presure | 7.6E-10mmHg at 25°C |
Appearance | Colorless crystal |
Storage Condition | 2-8℃ |
Refractive Index | 1.564 |
MDL | MFCD00145350 |
Physical and Chemical Properties | melting point 102.4°C |
Use | Triazole fungicides, highly effective fungicides for seed treatment or foliar spraying of important cash crops, can effectively control various rust diseases of cereal crops, etc. |
Hazard Symbols | Xn - Harmful N - Dangerous for the environment |
Risk Codes | R22 - Harmful if swallowed R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R63 - Possible risk of harm to the unborn child |
Safety Description | S2 - Keep out of the reach of children. S22 - Do not breathe dust. S36/37 - Wear suitable protective clothing and gloves. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
Reference Show more | 1. Xiao Suping, Zhong Rongrong, Gao Hui, et al. Rapid Determination of Eight Pesticide Residues in Different Dendrobium by Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry [J]. Modern Chinese Medicine, 2020, v.22(04):135-140 153. 2. [IF = 10.588] Jiangtao Dong et al."Cyclodextrin polymer-valved MoS2-embedded mesoporous silica nanopesticides towards hierarchical targets via multidimensional stimuli of biological and natural environments." J Hazard Mater. 2021 Oct;419:126404 |
triazole fungicides | tebuconazole is a triazole fungicide, which is a high-efficiency fungicide used for seed treatment or foliar spraying of important economic crops. Due to its strong absorption, it is used to treat seeds and can kill germs attached to the surface of seeds, and can also conduct to the top of crops to kill germs in crops. Used for foliar spray, it can kill the germs on the surface of the stems and leaves, and can also conduct upward in the crop body to kill the germs in the crop body. The sterilization mechanism is mainly to inhibit the biosynthesis of ergosterol of the pathogenic bacteria, which can prevent powdery powder, diseases caused by the genus Puccinia, Coracospora, Nucleoacia and Hysterospora. at present, tebuconazole is used as seed treatment agent and foliar spray all over the world, with wide bactericidal spectrum, not only high activity, but also long duration. Tebuconazole is mainly used to control a variety of fungal diseases on crops such as wheat, rice, peanuts, vegetables, bananas, apples, pears, and corn sorghum. It has been registered and widely used on more than 60 crops in more than 50 countries around the world. This product is used to prevent and control rape sclerotinia sclerotiorum. It not only has good control effect, but also has the characteristics of anti-lodging and obvious yield increase. The mechanism of action on the bacteria is to inhibit the demethylation of ergosterol on the cell membrane, making the bacteria unable to form Cell membrane, thereby killing germs. There are many studies on the synthesis of tebuconazole, most of which use p-chloroformaldehyde as the starting material to prepare tebuconazole through aldehydes and ketones condensation, catalytic hydrogenation, epoxidation reaction, addition reaction and other steps. |
mechanism of action | tebuconazole is a broad-spectrum triazole fungicide, the mechanism of action is sterol demethylation inhibitor, seed treatment or foliar spraying can prevent and control cereal crop rust, powdery mildew and smut and other diseases. However, the use of the fungicide in seed dressing or seedling stage is easy to cause inhibition on the growth of cereal crops, especially on corn seedlings. Continuous single use is easy to produce drug resistance and high cost of single use. |
preparation | CN200810101939.1 provides a preparation method of tebuconazole emulsion in water. The weight percentage of each component in the formula is: tebuconazole 1-25%, emulsifier 1-20%, antifreeze 1-5%, defoamer 0-2%, solvent 1-45%, thickener 0.1-3%, and the rest is water. The emulsifier is selected from one or more of NPE, AEO, 100#, 300#, 500#, 600#, 700#, BY (or EL), 2000#, 1600#, OT, 600# P2O5 → phosphate salt, NPE P2O5 → phosphate salt, Ci-acid ester. |
use | triazole fungicides are highly effective fungicides for seed treatment or foliar spraying of important cash crops, which can effectively prevent and control various rust diseases of cereal crops, etc |
EPA chemical information | Information provided by: iaspub.epa.gov (external link) |